Category Archives: Healthcare Technology

PrintRite3D Machine Health Module Beta Version Announced

SANTA FE, NM, Nov 4, 2022 – Sigma Additive Solutions, Inc., a leading developer of quality assurance software to the commercial 3D printing industry, announced today that it is releasing a beta version of the PrintRite3D Machine Health module. This new solution marks the beginning of the company’s software-only approach to quality assurance by allowing users to take disparate machine log files and standardize them. Built upon Sigma’s PrintRite3D monitoring and analytics technology, the company is creating a framework for connecting and standardizing distinct sensors and images into a cohesive product suite.

Machine Health from Sigma Additive Solutions (Graphic: Business Wire)

Features of the new solution include:

  • A path to scale for integrated sensor fusion of camera, thermal camera, melt pool data, and more
  • Ability to link machines by API or upload all machine sensor .csv log files
  • Creation of a common standards-based file format for analytics, visualization, and reporting, agnostic of machine type
  • A single cohesive environment for all in-process quality data, customizable to unique production requirements
  • Deep insight, analytics, and reporting of machine sensor data
  • Dashboard visualization showing key metrics

“This is an exciting announcement, not only for Sigma, but for the entire additive industry,” remarked Jacob Brunsberg, Sigma’s president and chief executive officer. He added, “Today, proprietary quality control approaches of various additive machine manufacturers often lead to inconsistency in quality assurance across manufacturing operations. The objective of the initial module, and all future modules, is to help drive a standards-based approach to additive manufacturing, allowing users to gain consistency across their sites and supply chains. Allowing users to take disparate machine log files and standardize them is an important first step in connecting distinct sensors and images into a cohesive product suite.”

“A truly holistic approach to quality is just what the industry needs,” stated Ivan Madera, chief executive officer of Morf3D. “As a member of the Sigma Additive Product Advisory Council, I am thrilled to have early access to the launch of the Machine Health and future modules, and to put them to work in our facility. Standardizing machine logs will streamline processes and advance digital quality workflows. Having a single interface, streaming data from all connected machines, moves the industry forward into a digital future and away from hours of work from manually collecting, converting, processing, and analyzing all the individual aspects of quality.”

Darren Beckett, CTO of Sigma, added: “Sensor fusion – conjoining data types – will provide improved confidence in defect detection, root cause analysis and mitigation, allowing everyone to interpret control charts and other data types/sources uniformly. Our engineering team has spent over 10 years developing the technology to provide a framework for standards-based data exchange, metrics, and analytics. We are committed to an open architecture philosophy and acting as a third-party agnostic option, connectable to the broader installed base of the additive industry.”

About Sigma Additive Solutions

Sigma Additive Solutions, Inc. is a leading provider of in-process quality assurance (IPQA) solutions to the additive manufacturing industry. Sigma specializes in the development and commercialization of real-time monitoring and analytics known as PrintRite3D for 3D metal and polymer advanced manufacturing technologies. PrintRite3D detects and classifies defects and anomalies real-time during the manufacturing process, enabling significant cost-savings and production efficiencies by reducing waste, increasing yield and shortening cycle times. Sigma believes its software solutions will be a major catalyst for the acceleration and adoption of industrial 3D printing.

For more information, please visit

Particle Works launches ALiS for LNP Formulation Screening

Particle Works continues to pave the way for particle perfection with the highly anticipated launch of its second revolutionary platform, the Automated Library Synthesis (ALiS) System. This innovative platform enables automation and high-throughput screening of lipid nanoparticle (LNP) formulations and mRNA candidates in early-stage drug development.

Liposomes and lipid nanoparticles are becoming increasingly important in a wide range of industries, particularly pharmaceuticals, where they can be used as drug delivery vehicles or to encapsulate vaccines, including for COVID-19. The systems currently used for candidate screening in early-stage drug development require formulations to be changed manually and lack the necessary automation to process large numbers of samples quickly. All that is set to change with the launch of the groundbreaking ALiS platform. Following on from the popular Automated Nanoparticle (ANP) System, ALiS fills a gap in the marketplace for customers wanting to significantly accelerate their formulation screening. It requires little to no manual intervention, increasing lab efficiency while retaining the consistency, monodispersity and high encapsulation efficiency that Particle Works’ platforms guarantee.

The pioneering ALiS platform, based on microfluidic technology, features a number of unique benefits. Its dedicated software enables walk-away processing of up to 96 unique formulations in a typical working day, aspirating from and dispensing into covered 96 well plates. Formulation specifications such as lipid ratios and reagent concentrations, as well as process parameters – including total flow rate and the flow rate ratio – can be varied from well to well, to quickly establish the ideal properties and responses for your application. The system also offers unparalleled flexibility for experimental design and has flexible control over collection volumes. Its Anti-dispersion Technology lets you work with smaller reagent volumes, maximizing the use of precious materials, minimizing evaporation, and allowing the collection of as little as 100 µl of reagent per experiment.

Gareth Bolitho, commercial manager at Particle Works, commented: “The days of labor-intensive screening work are over. This is groundbreaking technology for scientists working on nanoparticle formulation, developed in response to customer demand for automated, high-throughput screening, and has already been used to great effect at a major biotechnology company over the last 18 months. With accurate control, high encapsulation efficiency and consistent day-to-day performance, we are confident that ALiS will become the screening platform of choice for scientists working in drug discovery.”

Discover more about the novel ALiS platform for LNP formulation screening at

About Particle Works

Particle Works combines a strong heritage in engineering with nanoparticle knowledge, microfluidic expertise and in-house microfluidic chip fabrication. They design and manufacture state-of-the-art particle engineering platforms, paving the way to particle perfection.

Their technology is used in a wide range of applications, including the production of nanoparticle-based vaccines, medicines, and therapeutics. Recently spun out of the Dolomite Microfluidics brand, Particle Works was born as a dedicated and focused drug delivery brand. They have been at the forefront of this rapidly changing science, listening and adapting as their customers’ needs have evolved. Their platforms enable scientists to formulate particles faster, ensuring they are ready for their next breakthrough and the scale up of discoveries.

Particle Works is part of Blacktrace Holdings Limited – a world leader in Productizing Science – and is based in Royston (near Cambridge) UK. They have offices in the USA, Japan and Vietnam, and worldwide distributors offering technical assistance and support.